HomeCLC software: Important notificationsIssues affecting only versions of products released prior to June 2017Positive fold change instead of absolute fold change filtering in Cancer Research Workbench 1.5.x, 2.0 and Genomics Workbench 8.0

3.12. Positive fold change instead of absolute fold change filtering in Cancer Research Workbench 1.5.x, 2.0 and Genomics Workbench 8.0

The tool "Extract Differentially Expressed Genes" tool in the Cancer Research Workbench 1.5 and 2.0 and its counterpart tool in CLC Genomics Workbench 8.0 "Create Track from Experiment". 

This issue was fixed in the Cancer Research Workbench 1.5.4, Biomedical Genomics Workbench 2.1, and the CLC Genomics Workbench 8.0.1.

Both these tools have the facility to filter results based on various values, including fold change. Filtering on fold change is currently being done for values greater than the value provided in the Wizard. For example, in the images below, folder changes greater then 1.5 would be filtered for. What is commonly desired, however, is to filter on values that are either less than -1.5 or greater than 1.5, i.e. > abs(fold change).

 

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