The Download Genomes functionality of the Reference Data Manager of QIAGEN CLC Genomics Workbench goes out to third party URLs to access the data resources requested.
The most common causes hindering downloading genomes from external resources are listed below.
What to do if Download Genomes in the Reference Data Manager fails
1) If you are working at a site with a proxy setup
Check your proxy settings by trying out other tools in the Workbench that connect to external sites. One example of this is the "Search for Sequences at NCBI" tool, which is located under the Download button on the Workbench toolbar (https://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=References_management.html).
If this check fails too, you will need to configure your Workbench with the proxy information needed. How to enter proxy information into the Workbench is described in our manual here:
http://resources.qiagenbioinformatics.com/manuals/clcgenomicsworkbench/current/index.php?manual=Network_configuration.html
Once the settings are entered, please restart your Workbench and try using the Download Genomes tool again.
2) If your firewall prevents access to external URLs
In this case, please ensure that the required URLs are white listed by your local IT. The list of URLS being accessed by the Workbench are listed here:
Which internet addresses does CLC software need access to?
3) If your site has no proxy but the remote site with the data is not accepting connections at this time.
If this is the case, then trying again another time should solve the problem.
Please wait a little while, for example a half hour, and then try the Download Genomes tool again. If there was a problem at the external site where the data is being downloaded from, sometimes the site will become available again after a short while.
4) The remote site is blocking access from your site.
This is not very common, but can happen, e.q. if much data traffic has come from the same site.
If all the above suggestions do not work, then please:
- Restart your Workbench.
- Run Download Genomes again.
- When it fails, submit the error to the QIAGEN digital insight support team. How to submit error reports to us is described in the following FAQ entry:
How do I submit an error report for a CLC Workbench to the Support team?